FAQs About BCL6 & Endometriosis

What Is BCL6?

BCL6 is a protein marker highly associated with inflammation on the uterine lining. When the uterine lining is inflamed, it is most often caused by endometriosis. At MyReceptiva Myreceptiva.com, we offer a test specifically designed to detect BCL6 in the uterine lining.

What Is the Link Between BCL6 and Endometriosis?

BCL6 is induced by inflammation. Endometriosis is a form of uterine inflammation, Regardless of symptoms endometriosis may be present and BCL6 will identify it.. Silent Endometriosis is called silent because there are not as many noticeable symptoms. This is where BCL6 comes into the picture. When a patient tests positive for BCL6, they likely have endometriosis.

Can Silent Endometriosis Be a Cause for Unexplained Infertility?

Unexplained infertility is defined by a year or more of trying to get pregnant or having recurrent pregnancy losses, There are many factors doctors look at for unexplained infertility. One of the most common is endometriosis. When a patient is experiencing unexplained infertility, they may also be experiencing endometriosis without knowing it. Silent and symptomatic endometriosis can make it difficult for a fertilized egg to implant correctly. This is because the inflammation caused by endometriosis may not allow the egg to stick to the endometrial lining or develop correctly.

What Does Testing Look Like for BCL6?

MyReceptiva tests specifically for BCL6, which is linked to inflammation usually caused by endometriosis. The testing process begins with an endometrial biopsy done by an OB-GYN or a reproductive specialist. The test should take place during a natural cycle 7-10 days after ovulation. The sample is sent to our lab where our team will do a full pathology report and identify if BCL6 is present. A patient should receive their results within a 5-6 day range. Once the results are found, a patient can move forward with treatment or management tools if they are positive.

Who Should Get Tested?

In general, patients who have any of the following symptoms are great candidates for MyReceptiva:

Undiagnosed pelvic or abdominal pain.
Family history of endometriosis, pelvic or abdominal pain.
Pain during and after sex.
Getting up multiple times a night to urinate
Recurrent bladder or bowel pain.
High Body Mass Index (BMI) combined with non-specific symptoms such as anxiety, depression or fatigue.
Women 34 and under who have failed to conceive after 12 months of trying to conceive naturally.
Women 35 and over with unexplained infertility after 6 months of trying to conceive naturally.
Women with one or more consecutive miscarriages during the first 13 weeks of pregnancy.
Women and families wanting to screen before considering expensive next steps such as IVF.

BCL6 and Endometriosis

At MyReceptiva, we want our patients to understand everything there is to know about BCL6 testing and endometriosis. It can be frustrating not to have answers in regard to unexplained infertility. To learn more FAQs about BCL6 and endometriosis, visit MyReceptiva.com today.